Helu Cas: 146-56-5 Huihui Molekala: C20H21ClN2O4
| Lae hehee | 176-178°C |
| ʻO ka mānoanoa | 1.02 g/cm³ |
| ka mahana mālama | haehae ʻia ma ka lumi wela, ma waho o ka lā pololei a ma kahi wahi haʻahaʻa |
| hikiwawe | 50 mg/ml(I ka ethanol);Hiki ʻole i ka wai |
| hana ʻōpika | +111.6 degere (C=1, methanol) |
| Ka nana aku | keʻokeʻo a ʻaneʻane keʻokeʻo ka pauka kristal |
| Maemae | ≥97% |
'o ia ka "dihydropyridine calcium antagonist" (calcium antagonist, a i 'ole ka slow channel blocker) e pale ana i ka ne'e 'ana o "calcium ions" i na keena ma'i ma'i vascular a me na myocytes na'au.Hōʻike ka ʻikepili hoʻokolohua e pili ana me "nā kahua paʻa" no "dihydropyridines" a me "non-dihydropyridines".'O nā ka'ina hana 'contractile' o ka pu'uwai a me ka vascular smooth muscle e pili ana i ke komo 'ana o 'extracellular calcium ions' i loko o kēia mau pūnaewele ma o nā kaha ion kūikawā.keʻakeʻa nei i ke kahe ʻana o nā ion calcium ma waena o kēia mau memb cell, kahi hana e hoʻopilikia ai i nā ʻiʻo ʻiʻo maʻemaʻe vascular ma mua o nā cell cardiac.Hiki ke ʻike ʻia kahi hopena inotropic maikaʻi ʻole (Inotrope), a i ʻole ka hōʻemi ʻana i ka contractility myocardial, in vitro.Eia naʻe, ʻaʻole i ʻike ʻia kēlā mau hopena i nā holoholona i lawelawe ʻia i loko o ka nui o ka lāʻau lapaʻau i kuhikuhi ʻia.ʻAʻole pili ka nui o ka calcium i ka serum.I loko o ka pae pH physiological, he pūhui ionised (pKa = 8.6) nona ka launa pū ʻana me nā mea hoʻokipa calcium channel i hōʻike ʻia e ka holomua holomua o ka conjugation a me ka hoʻokaʻawale ʻana o ka mea hoʻokipa, a ʻo kēia ʻano holomua holomua ka hopena i kahi hopena holomua.
ʻO ia kahi vasodilator arterial peripheral e hana pololei ana i ka ʻiʻo maʻemaʻe vascular, e hopena i ka hoʻemi ʻana i ke kūʻē ʻana o nā kīʻaha peripheral a me ka emi ʻana o ke koko.ʻAʻole maopopo loa ke ʻano hana e hoʻomaha ai i ka angina, akā manaʻo ʻia e komo pū kēia: Exertional angina: I nā poʻe maʻi me ka angina exertional, NORVASC e hōʻemi i ka nui o ke kūpaʻa peripheral (ma hope o ka hoʻouka ʻana) i ka wā o ka hana naʻau i kēlā me kēia pae o ka hoʻoikaika kino a hoʻemi i ka helu. ʻO ka huahana kaomi, e hōʻemi ana i ka koi oxygen myocardial.
ʻO ka hoʻomaka ʻana he 5mg i kēlā me kēia lā, e hoʻonui i ka 10mg i kēlā me kēia lā.
