Azithromycin Cas helu: 83905-01-5 Molecular Formula: C38H72N2O12
Lae hehee | 115°C |
ʻO ka mānoanoa | 1.18 g/cm³ |
ka mahana mālama | ʻO ka lewa inert, lumi wela 2-8°C |
hikiwawe | DMF: 16 mg/ml DMSO: 5 mg/mlm Ethanol: 16 mg/ml Ethanol:PBS(pH 7.2) (1:1): 0.50 mg/ml |
hana ʻōpika | N/A |
Ka nana aku | Pauda keʻokeʻo |
Maemae | ≥98% |
Hāʻawi ʻo Manus Aktteva Biopharma LLP, kahi hui hoʻokele honua a me kahi mea hoʻolako o Azithromycin (CAS No.: 83905-01-5) hāʻawi no kāu mau koi o RND / Development nui a i ʻole nā mea kūʻai aku, e pili ana i ke kūlana o ka huahana.
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ʻO Azithromycin kahi erythromycin semi-synthetic, hoʻonui i ke apo i hana ʻia e kahi Beckmann rearrangement o ka erythromycin oxime a hoʻemi i ka imine ether, a ukali ʻia e ka methylation reductive.ʻO Azithromycin ka mua o nā azalides a ua hoʻolālā ʻia e hoʻomaikaʻi i ke kūpaʻa a me ka hapalua ola o ka erythromycin A, a me ka hoʻomaikaʻi ʻana i ka hana kūʻē i ka bacteria Gram negative.Mai kona loaʻa ʻana ma 1980 e Djokic a me nā hoa hana, ua hauʻoli ʻo azithromycin i ka kūleʻa therapeutic nui.