Ka helu helu: 21187-98-4 Molecular Formula
| Lae hehee | 163-169 °C |
| ʻO ka mānoanoa | 1.2205 (manaʻo koʻikoʻi) |
| ka mahana mālama | ʻO ka lewa inert, lumi wela 2-8°C |
| hikiwawe | methylene chloride: hiki ke hoʻoheheʻe |
| hana ʻōpika | N/A |
| Ka nana aku | Paʻa Keʻokeʻo Paʻa |
| Maemae | ≥98% |
he lāʻau antihyperglycemic waha i hoʻohana ʻia no ka mālama ʻana i ka maʻi mellitus type II.Aia ia i ka papa sulfonylurea o ka insulin secretagogues, ka mea e hoʻoulu ai i nā cell β o ka pancreas e hoʻokuʻu i ka insulin.hoʻopaʻa ʻia i ka β-cell sulfonyl urea receptor (SUR1), e ālai hou ana i nā ala pāpaʻi koʻikoʻi ATP.No laila, ke emi nui nei ka hoʻoheheʻe ʻana o ka pālolo, e hoʻemi ana i ka depolarization o nā cell β.A laila ua wehe ʻia nā kahawai calcium e pili ana i ka volta i loko o ka cell β, ka hopena i ka hoʻoulu ʻana o ka calmodulin, a laila e alakaʻi i ka exocytosis o ka insulin i loaʻa nā granules huna.Ua hōʻike pū ʻia nā haʻawina hou e hiki ke hoʻomaikaʻi maikaʻi i ke kūlana anti-oxidant a me ka nitric oxide-mediated vasodilation i ka maʻi diabetes Type 2 a pale aku i nā pancreatic beta-cell mai ka pōʻino e ka hydrogen peroxide.
he lāʻau hypoglycemic waha i hoʻohana ʻia no ka mālama ʻana i ka maʻi diabetes mellitus ʻole i pili i ka insulin. Ka mālama ʻana i ka maʻi diabetes e pili ana i ka momona a i ʻole ka maʻi vascular, no nā pākeke me ka maʻi maʻi type 2. ʻO ka maʻi diabetes kahi maʻi olakino maʻamau (lōʻihi) e pili ana i ka huli ʻana o kou kino ai i ka ikehu.e hoemi ana i ka nui o ka glucose o ke koko ma o ka hooulu ana i ka huna ana o ka insulin mai na β-cell o na mokupuni o Langerhans.
