Ka helu helu: 171599-83-0 Hui Māmā: C 2 2 H 3 0 N 6 O 4 S·C 6 H 8 O 7 = 666.70
| Lae hehee | 49-53° |
| ʻO ka mānoanoa | 1.05 g/cm³ |
| ka mahana mālama | wahi anuanu, maloʻo a pale i ka ʻike ʻana i ka mālamalama a i ʻole ka wela wela |
| hikiwawe | hiki ke hoʻoheheʻe ʻia i ka ethanol, acetone, etera, benzene a me methylene chloride, akā hiki ʻole ke hoʻoheheʻe ʻia i ka wai. |
| hana ʻōpika | [α]D20 = +61.0° (hoʻoheheʻe ethanol) |
| Ka nana aku | keʻokeʻo a ʻulaʻula melemele crystalline pauda |
I ka wā o ka hoʻoulu ʻana i ka moekolohe, hoʻokuʻu ke aʻalolo parasympathetic, non adrenergic and non cholinergic nerve (NANC) a me nā cell endothelial vascular i ka nitric oxide (NO) ma lalo o ka hana a nitric oxide synthase (NOS).I loko o nā kīʻaha koko, hoʻohana pinepine ʻia ka soluble guanylate cyclase (sGC) e NO, a hana ka sGC i ka guanosine triphosphate e hana i ka cGMP.ʻO ka cGMP i loko o ka corpus cavernosum o ka penis e hoʻoikaika i ka hopena vasodilator ma o ka hoʻohaʻahaʻa ʻana i ka neʻe ʻana o Ca2+ i loko o nā puʻupuʻu ʻiʻo maʻemaʻe o ka corpus cavernosum, e hoʻomaha ai i nā ʻiʻo maʻemaʻe a me ka piʻi ʻana o ke kahe o ke koko i loko o ka corpus cavernosum, alakaʻi. i ke kukulu ana.Hoʻemi ʻo Jinyang alkali i ke kiʻekiʻe o ka degradation o cGMP, a laila mālama i ka hopena hoʻomaha o cGMP ma ka corpus cavernosum o ka penis a me ka hoʻokumu ʻana i ka penile.I loko o vivo, hoʻohaʻahaʻa ʻia ka cGMP a hoʻopau ʻia e PDE5.
He kūpono no ka mālama ʻana i ka erectile dysfunction (ED) o ka penis, he kūpono ia no ka erectile dysfunction ma muli o ka hoʻohana ʻana i nā antidepressants, antipsychotics, a me nā lāʻau antihypertensive, a me ka erectile dysfunction i hoʻokumu ʻia e ka ʻoki a i ʻole ka trauma.
Hiki ke hana ia i papa, pills, hard capsules, soft capsules, a hiki ke hoohana ia e like me ka waina lapaau, ka wai waha, kofe, granules, chewable tablets, lozenges, chewing gum, and other dosage forms.No ka poʻe mākua, ʻo 10-100mg ka nui i kēlā me kēia lā, hiki ke hoʻonui a hoʻemi ʻia e like me ke kūlana o ka mea hoʻohana.ʻOi aku ka maikaʻi o ka lawe ʻana ma ka ʻōpū ʻole (ʻoi aku ka pale ʻana i ka lawe ʻana me ka meaʻai momona nui), a mai inu i ka waiʻona ma mua o ka hoʻohana ʻana i ke kī (ʻaʻole pono e ʻai ʻia i ka manawa like, ʻaʻole ia he manaʻo e inu i ka waiʻona i ka manawa like. hiki i ka manawa ke hōʻemi nui i ka hana erectile o Viagra).
Ka manawa kūpono: Lawe ka hapa nui o ka poʻe i hoʻokahi hola e hoʻokō ai.Manaʻo ʻia e lawe i ka lāʻau lapaʻau ma kahi o 1 hola ma mua o ka moe kolohe ʻana, me kona mau hopena e mau ana no 48 a 72 mau hola, a hiki i kekahi ke mau no 116 hola.
